Although Airflo™ is generally considered safe, it is important to note certain precautions before use. If you experience difficulty breathing through your nose, it is advised not to use Airflo™. Furthermore, if you are obese with a BMI over 35, it should not be used as a standalone solution without a CPAP device. It is also not recommended for individuals with very low blood pressure, severe heart or breathing problems, or those currently dealing with a cold, sinus, or ear infection. Additionally, refrain from using Airflo™ if you have severely chapped lips or any non-intact skin surrounding the mouth area. Lastly, it is advisable to avoid using Airflo™ mouth tape after consuming alcohol or sedatives.